Table 1.
Demographic characteristics of GRN carriers (aGRN+) and controls (GRN−)
Baseline visit (T0) | Follow-up visit (T20) | |||||
Genetic status | aGRN+ | GRN− | p-value | aGRN+ | GRN− | p-value |
Number of cases | 16 | 17 | – | 14 | 14 | – |
Gender Male/Female | 4/12 | 6/11 | – | 4/10 | 5/9 | – |
Education level (mean score) | 2.7±0.5 | 2.8±0.5 | 0.8 | – | – | – |
Age at examination, | 41.9±8.2 | 40±8.3 | 0.8 | 43±7.9 | 42.1±9.0 | 0.9 |
years (range) | (27–58) | (27–60) | (28–59) | (29–51) | ||
Duration T0–T20, months | – | – | – | 19.5±2 | 20.0±6.2 | 0.9 |
Distance to estimated age at | 20±10 | – | – | – | – | – |
onset, years (range) | (7–34) |
Means ± SD are reported. Significant p-value <0.05. Educational level has been scored as follow: score 1 (5–8 years of study); score 2 (9–12 years); score 3 (>12 years).