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. 2015 Jun 1;5(2):301–311. doi: 10.3233/JPD-140509

Fig.2.

Fig.2

EFS-induced bladder responses in bladder strips in controls and 6-OHDA-lesioned rats. Following EFS the bladder strips from 6-OHDA-lesioned rats (n = 16) showed an overall significantly higher contractile response as compared to controls (n = 26; A, B). In the presence of atropine the EFS response was reduced in both groups by 31% and 33% for controls and 6-OHDA respectively (C). However a significant difference could still be observed at 40 Hz. Following administration of phentolamine (10 − 5M) together with suramin and atropine, no change in contraction in the control (n = 7) as compared to 6-OHDA (n = 7) was observed (p = 0.094; D). The grey thin line under the responses in panel C represent the duration of the electric stimulation.  * = significantly different from control group. [Two-way repeated ANOVAs; (A) interaction: F(5, 200) = 3.86, p = 0.00023, Group: F(1, 40) = 4.15, p = 0.048; (C) interaction: F(5, 200) = 2.86, p = 0.016, Group: F(1, 40) = 1.96, p = 0.17; (D) interaction: F(5, 60) = 1.98, p = 0.094, Group: F(1, 12) = 3.09, p = 0.10. All ANOVAS are followed by a Bonferroni multiple comparison test].