FIG. 3.

Sequence alignment of the general amino acid permeases of P. chrysogenum (PcGap1), S. cerevisiae (Gap1) (24), C. albicans (CaGap1) (6), Aspergillus fumigatus (AfGap1), and N. crassa (NcGap1; encoded by the pmg locus) (28). AfGap1 is a putative general amino acid permease, based on its homology with PcGap1 (78% amino acid identity) and Gap1 (55% identity), and was obtained from the A. fumigatus Genome Database at The Institute for Genomic Research after a BLAST search (2). NcGap1 was originally deposited with GenBank as NAAP1. Conserved and similar amino acids are highlighted in black and grey, respectively.