. 2016 Jun 28;6:28796. doi: 10.1038/srep28796

Table 5. Pharmacokinetic parameters of CUR eye drops and NLCs in rabbit tears (mean ± S.D., n = 6).

Group	C_max (μg/mL)	AUC_(0-∞) (μg/mL/min)	MRT_(0-∞)(min)
Eye drops	16.58 ± 1.98	606.95 ± 25.23	48.42 ± 10.20
NLC	64.36 ± 2.25^a	3622.32 ± 59.51^a	61.73 ± 1.79^a
CH-NLC	87.62 ± 2.68^a,^b	7435.69 ± 379.39^a,^b	106.21 ± 16.51^a,^b
CS-NAC_H-NLC	147.36 ± 4.93^a,^b,^c	18134.61 ± 863.72^a,^b,^c	141.14 ± 15.45^a,^b,^c

^aStatistically significant compared with the eye drops (p < 0.05).

^bStatistically significant compared with the NLC (p < 0.05).

^cStatistically significant compared with the CH-NLC (p < 0.05).