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. 2016 Jun 28;6:28773. doi: 10.1038/srep28773

Figure 5. BDMC inhibited the extracellular matrix degradation-associated proteins.

Figure 5

(A,D,E) The cells were treated with various concentrations of BDMC for 24 h. The cell lysate was prepared and used to analyze expression levels of MMP-2/9, TIMP-1, ICAM-1, VCAM-1, uPA and CD147 using western blot analysis. The intensity of protein bands was quantified by densitomety. (B,C) MMP-2/9 activity was determined by Activity Assay Kit, respectively. BDMC, Bisdemethoxycurcumin. The data represent as mean ± SEM. *p < 0.05, **p < 0.01 vs. control group.