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. 2016 Jun 28;6:28693. doi: 10.1038/srep28693

Figure 2. Differentially expressed microarray probes (p < 0.05) and changes in muscle fibre type-specific gene expression in porcine Longissimus Dorsi muscle during 1–27 days of treatment with anabolic agents.

Figure 2

Numbers in the overlapping section of the venn diagrams represent shared differentially expressed probes by treatment with a beta-adrenergic agonist (grey circles; BA) and recombinant growth hormone (black circles; GH) (A). Porcine Longissimus Dorsi muscle transcript abundance of myosin heavy chain isoform genes during 1–27 days exposure to beta-adrenergic agonist (grey bars; BA) or recombinant growth hormone (black bars; GH) treatment compared to a control cohort (white bars; C); Myosin heavy chain I: Myh7 (B), Myosin heavy chain IIA: Myh2 (C), Myosin heavy chain IIX: Myh1 (D), myosin heavy chain IIB: Myh4 (E). Metabolic genes Enolase 3: Eno3 (F), and Isocitrate dehydrogenase 2: Idh2 (G), were measured as indicators of glycolytic and oxidative gene expression, respectively. Data is mean ± SEM. n = 10 for days 1, 3, 7 and 13, whilst n = 15 for day 27. *Indicates a significant treatment effect with p < 0.001 (unless otherwise stated). #Indicates a significant treatment x time interaction with p < 0.05.