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. 2011 Jul 21;58(1):97. doi: 10.1016/S0377-1237(02)80034-X

TABLE 1.

Comparison of pharmacotherapeutic agents in relief of allergic symptoms

Anti-Hl (sneezing, itching) Anti-Ach (rhinorrhoea) Sedation Nasal obstruction Eye Symptoms
First generation
Chlorpheniramine (Avil) ++ ++ + +
Triprolidine (Acrified) ++ ++ + +
Cyproheptadine (Periactin) ++ ++ ++ +
Promethazine (Phenergan) +++ +++ +++ +
Second generation
Terfenadine +++ +
Astemizole +++ +
Fexofenadine +++ +
Cetrizinc +++ + +
Topical antihistamine
Azelastine ++ ++ +