TABLE 1.
Comparison of pharmacotherapeutic agents in relief of allergic symptoms
| Anti-Hl (sneezing, itching) | Anti-Ach (rhinorrhoea) | Sedation | Nasal obstruction | Eye Symptoms | |
|---|---|---|---|---|---|
| First generation | |||||
| Chlorpheniramine (Avil) | ++ | ++ | + | + | |
| Triprolidine (Acrified) | ++ | ++ | + | − | + |
| Cyproheptadine (Periactin) | ++ | ++ | ++ | − | + |
| Promethazine (Phenergan) | +++ | +++ | +++ | − | + |
| Second generation | |||||
| Terfenadine | +++ | − | + | ||
| Astemizole | +++ | − | − | − | + |
| Fexofenadine | +++ | − | • | + | |
| Cetrizinc | +++ | − | + | − | + |
| Topical antihistamine | |||||
| Azelastine | ++ | ++ | − | + | − |