TABLE 1.
Comparison of pharmacotherapeutic agents in relief of allergic symptoms
Anti-Hl (sneezing, itching) | Anti-Ach (rhinorrhoea) | Sedation | Nasal obstruction | Eye Symptoms | |
---|---|---|---|---|---|
First generation | |||||
Chlorpheniramine (Avil) | ++ | ++ | + | + | |
Triprolidine (Acrified) | ++ | ++ | + | − | + |
Cyproheptadine (Periactin) | ++ | ++ | ++ | − | + |
Promethazine (Phenergan) | +++ | +++ | +++ | − | + |
Second generation | |||||
Terfenadine | +++ | − | + | ||
Astemizole | +++ | − | − | − | + |
Fexofenadine | +++ | − | • | + | |
Cetrizinc | +++ | − | + | − | + |
Topical antihistamine | |||||
Azelastine | ++ | ++ | − | + | − |