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. 2016 Jun 28;6:28990. doi: 10.1038/srep28990

Figure 8. Faecal samples were collected from wild-type C57BL/6 mice fed a HFD or normal chow diet (Con) for 22 weeks and treated with recombinant IL-22 (20 ng/g or 100 ng/g dose) for 4 weeks.

Figure 8

(a) Levels of total microbial (16S rRNA), Prevotella spp, A. muciniphila and E. coli were determined in the DNA extracted from faecal samples. n = 4 per group. Data presented as mean ± SD. One-way ANOVA with Bonferroni post-test multiple comparisons. *p < 0.05 **p < 0.01 ***p < 0.001. (b) Bray-Ward phylocluster analysis was used to determine the overall shifts in microbial population in Con, HFD and HFD mice treated with IL-22. Mean of n = 4 per group.