Table 1. Enzyme and cell-based assays profile of (-)-SCR1693.

Assay	Test Concentration (M)	% Inhibition of Control Values	% of Control Values			Reference Compound	IC50 Ref (M)	nH Ref
			1st	2nd	Mean
CDK5 /p35	3.0E-05	−5	105.2	104.1	104.6	staurosporine	2.1E-08	1.2
GSK3beta	3.0E-05	−3	106.4	98.8	102.6	staurosporine	9.9E-08	1.6
MARK1	3.0E-05	−4	100.7	107.8	104.2	staurosporine	1.5E-08	2.9
MARK2	3.0E-05	7	93.5	91.5	92.5	H-89	8.3E-06	2.9
MARK3	3.0E-05	4	95.8	96.9	96.3	staurosporine	1.7E-08	1.6
MARK4	3.0E-05	2	98.5	97.1	97.8	hymenialdisine	3.6E-08	1.4