Table 3. OR values for the UTUC subgroups according to clinical characteristics.
Outcome of interest | Studies | Patients | OR | 95% CI | P value | Model | Heterogeneity |
---|---|---|---|---|---|---|---|
I2, P value | |||||||
Ta/1 vs. T2-4 | 9 | 2,462 | 3.12 | 1.85–5.27 | 0.000 | Random | 86%, 0.000 |
High grade vs. Low grade | 3 | 799 | 1.66 | 1.20–2.29 | 0.002 | Fixed | 32%, 0.23 |
G3 vs. G1 + G2 | 2 | 921 | 1.42 | 0.75–2.69 | 0.28 | Random | 76%, 0.04 |
G2 + G3 vs. G1 | 2 | 921 | 0.94 | 0.49–1.79 | 0.85 | Fixed | 0%, 0.42 |
Lymph node metastasis vs. No lymph node metastasis | 6 | 1,834 | 1.60 | 1.13–2.26 | 0.009 | Fixed | 0%, 0.55 |
Renal pelvis vs. Ureter | 10 | 2,858 | 4.28 | 2.91–6.30 | 0.000 | Random | 78%, 0.000 |
Recurrence vs. No recurrence | 2 | 737 | 1.28 | 0.92–1.77 | 0.14 | Fixed | 0%, 0.68 |
Gender (Male vs. Female) | 7 | 2,556 | 1.01 | 0.86–1.19 | 0.90 | Fixed | 6%, 0.38 |
Notes.
Abbreviations
- CI
- confidence interval
- Fixed
- fixed, inverse variance model
- I2
- I-squared
- OR
- odds ratio
- Random
- random, I–V heterogeneity model