Table 2.
Variables | EAT mRNA levels | Serum levels | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Univariate | Multivariate (R 2 = 0.419, P < 0.001) | Univariate | Multivariate (R 2 = 0.246, P = 0.029) | |||||||||
Beta | 95 % CI | P value | Beta | 95 % CI | P value | Beta | 95 % CI | P value | Beta | 95 % CI | P value | |
Age | 0.01 | −0.33 to 0.35 | 0.946 | 0.10 | −0.19 to 0.39 | 0.492 | −0.27 | −0.58 to 0.05 | 0.095 | −0.23 | −0.53 to 0.07 | 0.132 |
Sex | 0.27 | −0.06 to 0.60 | 0.102 | 0.10 | −0.17 to 0.37 | 0.463 | 0.30 | −0.01 to 0.61 | 0.060 | 0.15 | −0.12 to 0.42 | 0.272 |
WC | −0.45 | −0.73 to −0.14 | 0.005 | −0.12 | −0.42 to 0.19 | 0.445 | −0.36 | −0.66 to −0.05 | 0.024 | −0.16 | −0.47 to 0.15 | 0.308 |
CAD | −0.66 | −0.90 to −0.40 | <0.001 | −0.57 | −0.89 to −0.24 | 0.001 | −0.59 | −0.86 to −0.33 | <0.001 | −0.35 | −0.67 to −0.03 | 0.036 |
T2DM | −0.36 | −0.68 to −0.04 | 0.029 | −0.11 | −0.39 to 0.17 | 0.438 | −0.29 | −0.60 to 0.03 | 0.072 | |||
TC | −0.11 | −0.24 to 0.47 | 0.520 | 0.36 | 0.05 to 0.66 | 0.024 | 0.23 | −0.04 to 0.50 | 0.093 | |||
HTN | −0.26 | −0.57 to 0.07 | 0.127 | −0.32 | −0.63 to −0.01 | 0.046 | −0.02 | −0.35 to −0.31 | 0.887 | |||
HOMA-IR | −0.21 | −0.53 to 0.12 | 0.210 | −0.32 | −0.64 to −0.01 | 0.041 | −0.15 | −0.48 to 0.17 | 0.350 |
Multivariate linear regression model includes age, sex and other variables with P < 0.05 in univariate analysis
EAT epicardial adipose tissue, CI confidence interval, WC waist circumference, CAD coronary artery disease, TC triglycerides, HTN hypertension, T2DM type 2 diabetes, HOMA-IR homeostasis model assessment of insulin resistance