Table 1.
Relationship between clinicopathological factors and PNI
| Variables | n (%) | PNI, mean ± SD | P value | |
|---|---|---|---|---|
| Age (year) | ≦65 | 102 (48) | 53.1 ± 4.1 | <0.001 |
| >65 | 110 (52) | 50.8 ± 5.2 | ||
| Histology | Ductal | 191 (90) | 51.9 ± 4.7 | 0.291 |
| Lobular | 9 (4) | 49.2 ± 5.0 | ||
| Special | 12 (6) | 53.4 ± 6.2 | ||
| Tumor size (cm) | ≦2 | 145 (68) | 52.3 ± 4.8 | 0.166 |
| >2, ≦5 | 61 (29) | 50.9 ± 5.0 | ||
| >5 | 6 (3) | 51.7 ± 4.0 | ||
| Nodal metastasis | 0 | 168 (79) | 52.0 ± 5.0 | 0.240 |
| 1–3 | 28 (13) | 52.0 ± 4.4 | ||
| >3 | 16 (8) | 50.1 ± 3.7 | ||
| Stage | 0/I | 135 (64) | 52.3 ± 4.8 | 0.124 |
| II | 58 (27) | 51.5 ± 4.9 | ||
| III | 19 (9) | 50.5 ± 4.5 | ||
| Estrogen receptor status | Positive | 168 (79) | 51.8 ± 5.0 | 0.682 |
| Negative | 44 (21) | 52.3 ± 4.4 | ||
| Progesterone receptor status | Positive | 145 (68) | 51.8 ± 5.0 | 0.879 |
| Negative | 67 (32) | 52.1 ± 4.6 | ||
| HER2 status | Positive | 39 (18) | 51.0 ± 4.8 | 0.152 |
| Negative | 173 (82) | 52.1 ± 4.8 | ||
| CEA (ng/ml) | <5 | 164 (77) | 51.9 ± 4.6 | 0.953 |
| ≥5 | 48 (23) | 51.9 ± 5.5 | ||
| CA 15-3 (U/ml) | <23 | 199 (94) | 52.0 ± 4.8 | 0.327 |
| ≥23 | 13 (6) | 50.4 ± 5.1 |
PNI prognostic nutritional index, ER estrogen receptor, PR progesterone receptor, HER-2 human epidermal growth factor receptor 2