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. 2016 Jun 28;18:68. doi: 10.1186/s13058-016-0725-1

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Representative images of cases with discordant ER, PR, and HER2 status between any two cores from the same case due to presence of benign epithelium (arrows for ER, PR) and clinging ductal carcinoma in situ (HER2). Percentage of ER- and PR-positive cells or HER2 status is indicated for each core. ER estrogen receptor, HER2 human epidermal growth receptor 2, PR progesterone receptor