Table 2.

Clinical characteristics of the 34 Taiwanese patients with MPS II who died between 1995 and 2012

Clinical characteristics	Number (%)
Age at onset of symptoms (years) (n = 32)	2.5 ± 2.1
Age at diagnosis (years) (n = 32)	4.8 ± 3.1
Gestational age (weeks) (n = 24)	39.2 ± 1.8
Birth weight (gram) (n = 24)	3522 ± 581
Birth weight (SDS) (n = 24)	0.56 ± 1.30
Primary cause of death, n (%)
Respiratory failure	19 (56 %)
Cardiac failure	6 (18 %)
Post-traumatic organ failure	1 (3 %)
Infection (sepsis)	1 (3 %)
Unknown	7 (21 %)
Age at death (years)	14.2 ± 4.2
Age at death, n (%)
<5 years	0
≧5 to <10 years	5 (15 %)
≧10 to <15 years	16 (47 %)
≧15 to <20 years	11 (32 %)
≧20 years	2 (6 %)
Year of death, n (%)
1995–2000	4 (12 %)
2001–2004	10 (29 %)
2005–2008	10 (29 %)
2009–2012	10 (29 %)
Phenotype, n (%)
Severe	31 (91 %)
Intermediate	1 (3 %)
Mild	2 (6 %)
ERT, n (%)
Yes	2 (6 %)
No	32 (94 %)
HSCT, n (%)
Yes	2 (6 %)
No	32 (94 %)

MPS mucopolysaccharidosis, SDS standard deviation score, ERT enzyme replacement therapy, HSCT hematopoietic stem cell transplantation