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. 2016 Jun 27;23:49. doi: 10.1186/s12929-016-0266-z

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — The deficit on nest construction displayed by APP/PS1 mice were improved by HE-My treatment. Five months old wild type (WT) or APP/PS1 mice were orally administered with vehicle (Veh, n = 6) or HE-My (n = 6) for 81 days and then nest construction test were performed. The representative images of the nest construction (a), the nest score (b) and unshredded nestlet (c) were shown. The results are the mean ± SD. Significant differences between WT (n = 8) and APP/PS1 groups are indicated by **, p < 0.01; ***, p < 0.001. Significant differences between treated and control (Veh) groups are indicated by #, p < 0.05