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. 2016 Jun 27;9:38. doi: 10.1186/s13048-016-0248-5

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Analysis of cytotoxic CRAd effects in normal and OvCa cells. a) The monolayers of normal ovarian surface epithelial IOSE-120 and IOSE-523 cells or OV-4 and OVCAR3 OvCa cells were infected with each CRAd vector at the indicated MOIs (vp/cell). b) The monolayers SKOV3ip.1 and SKOV3luc OvCa cells were infected with each CRAd alone (left panel) or two CRAd vectors together (right panel) at the indicated MOIs (vp/cell). The infected and uninfected cells were stained using MTS-based Cell Proliferation Assay (Promega) 6 days postinfection to detect cells that survived CRAd CPE. Live cells percentages are calculated with respect to mock-infected cell monolayers.. Each data point represents the cumulative mean ± SD (some error bars are smaller than the symbols, p ≤ 0.05)