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. 2016 Jun 27;23:50. doi: 10.1186/s12929-016-0267-y

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — NAD + −induced AP shortening in the presence of phospholipases inhibitors. a relative APD90 at the moment of maximal AP shortening induced by 10 μM NAD+ in normal conditions and in the presence of PLC inhibitor U73122 (0.1 μM) or PLD inhibitor FIPI (0.1 μM). APD90 is expressed in % of control APD90. * - significant effect of NAD+, p < 0.05, Wilcoxon test. & - significant difference between the columns, p < 0.05, Mann–Whitney test. b, c representative traces of APs before and during NAD+ application in the presence of U73122 (b) or FIPI (c)