Table 4.
Multivariate analysis of factors associated with fertility and sexual health discussions, and fertility preservation
| Fertility discussion | Sexual health discussion | Fertility preservation | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Category | Level | OR | 95% CI | P‐Value | Global P ‐Value | OR | 95% CI | P ‐Value | Global P‐Value | OR | 95% CI | P‐Value | Global P‐Value |
| Age+ | <31 | 1 | – | – | – | 1 | – | – | – | 1 | – | – | – |
| 31–34 | 1.05 | 0.57–1.93 | 0.61 | 0.68 | 3.72 | 0.94–14.72 | 0.25 | 0.05 | 0.69 | 0.31–1.49 | 0.16 | 0.01 | |
| 35–38 | 1.06 | 0.60–1.89 | 0.50 | 2.01 | 0.51–7.99 | 0.48 | 0.43 | 0.20–0.91 | 0.73 | ||||
| 39+ | 0.74 | 0.37–1.47 | 0.24 | 5.58 | 1.37–22.76 | 0.02 | 0.16 | 0.05–0.55 | 0.01 | ||||
| ECOG+ | 0 | 1 | – | – | – | 1 | – | – | – | 1 | – | – | – |
| 1 or 2 | 1.27 | 0.70–2.33 | 0.43 | – | 1.03 | 0.33–3.24 | 0.96 | – | 1.83 | 0.65–5.17 | 0.25 | – | |
| Relationship status | Single | 1 | – | – | – | – | – | – | – | – | – | – | – |
| Partner | 1.59 | 0.97–2.60 | 0.06 | – | – | – | – | – | – | – | – | – | |
| Children at initial consultation | Had children | – | – | – | – | – | – | – | – | 1 | – | – | – |
| No children | – | – | – | – | – | – | – | – | 3.13 | 1.64–5.98 | 0.0005 | – | |
| Family History of cancer among 1st degree relatives+ | No | 1 | – | – | – | 1 | – | – | – | – | – | – | – |
| Yes | 1.37 | 0.87–2.16 | 0.17 | – | 1.82 | 0.84–3.98 | 0.13 | – | – | – | – | – | |
| Tumor group+ | Breast | 1 | – | – | – | 1 | – | – | – | 1 | – | – | – |
| testicular | 0.94 | 0.58–1.53 | 0.31 | 0.35 | 1.38 | 0.47–4.03 | 0.32 | 0.001 | 3.43 | 1.74–6.78 | 0.007 | 0.002 | |
| Gynecological | 1.44 | 0.81–2.57 | 0.15 | 5.13 | 2.17–12.12 | 0.001 | 2.11 | 0.97–4.59 | 0.72 | ||||
| Treatment site | Other | – | – | – | – | – | – | – | – | 1 | – | – | – |
| Teaching hospital | – | – | – | – | – | – | – | – | 1.80 | 0.97–3.56 | 0.06 | – | |
| Sexual health discussion at initial consultation | No | 1 | – | – | – | – | – | – | – | – | – | – | – |
| Yes | 3.06 | 1.20–7.87 | 0.02 | – | – | – | – | – | – | – | – | – | |
| Fertility discussion at Initial consultation | No | – | – | – | – | – | – | – | – | 1 | – | – | – |
| Yes | – | – | – | – | – | – | – | – | 13.06 | 5.75–29.62 | <0.0001 | – | |
Note that a backwards selection procedure was used to refine the models so that covariates that did not significantly improve model fitness as per the likelihood ratio test were removed one at a time.
ECOG, Eastern Cooperative Oncology Group.
Bold values represent statistically significant values on multivariate analysis.