Figure 1.

Loss of mast cells reduces mammary tumor growth. (A) Breeding and experimental Scheme. (B) Mammary tumor onset is similar between PyMT/WT and PyMT/Kit^{W‐sh/W‐sh} female mice. Nineteen PyMT/wild‐type (WT) mice (n = 19) and 15 PyMT/Kit^{W‐sh/W‐sh} mice (n = 15). P = 0.54. (C) Mammary tumor growth is reduced in PyMT/Kit^{W‐sh/W‐sh} mice compared with PyMT/WT mice. After palpable tumors were detected, four mice (n = 4) for each group were monitored for their tumor growth with digital caliper for 10 weeks. *P < 0.05.