Table 4.
Sex | Age (years) | HP | Therapy | Time to relapse (months) | HP reinfection | Local of relapse | Relapse therapy | Response | Additional therapies | End of follow-up | DFS (months) | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | F | 45 | Yes | HP eradication | 14 | Yes | Gastric | HP eradication | No remission | RCHOP Radiation | Alive without disease | 41 |
2 | F | 29 | Yes | HP eradication | 15 | Yes | Gastric | HP eradication | Remission | Alive without disease | 153 | |
3 | M | 58 | Yes | HP eradication | 30 | No | Upper limb mass and perigastric lymph nodes | RCHOP | Remission | Alive without disease | 37 | |
4 | M | 69 | Yes | HP eradication | 89 | Yes | Gastric | HP eradication | Remission | Alive without disease | 6 | |
5 | M | 61 | Yes | HP eradication | 14 | No | Gastric and perigastric lymph nodes | CVP | Remission | Dead without disease | 114 | |
6 | M | 57 | No | HP eradication Chlorambucila | 24 | No | Gastric | Rituximab | Remission | Radiation (2nd relapse) | Alive without disease | 44 |
7 | F | 46 | No | HP eradication Chlorambucila | 16 | No | Gastric | RCHOP | Remission | Alive without disease | 56 | |
8 | M | 49 | Yes | HP eradication | 11 | No | Gastric | Radiation | Remission | Alive without disease | 37 | |
9 | F | 42 | Yes | HP eradication | 9 | Yes | Gastric | HP eradication | Remission | Alive without disease | 29 | |
10 | M | 56 | Yes | HP eradication | 11 | Yes | Gastric | HP eradication | Remission | Chlorambucil (2nd relapse) RCVP (3th relapse) | Alive without disease | 33 |
11 | F | 78 | Yes | HP eradication | 4 | Yes | Gastric | HP eradication | Remission | Alive without disease | 18 |
CVP: cyclophosphamide, vincristine, prednisone; DFS: disease free survival; F/M: female/male; HP: Helicobacter pylori; RCHOP-rituximab, cyclophosphamide, doxorubicin (hydroxydaunomycin), vincristine (oncovin), prednisolone; RCVP: rituximab, cyclophosphamide, vincristine, prednisone.
These patients did not achieve complete remission after HP eradication and watch-and-wait strategy, and thus received an alternative therapy.