Table 3.
Associated factors for the eradication success in each regimen
| Eradicated | Not-eradicated | p-value | |
|---|---|---|---|
| 10-day regimen | (n = 10) | (n = 2) | |
| H. pylori status | |||
| Presence of mutation in rpoB, n (%) | 1 (10.0) | 0 (0) | 1a |
| Rifabutin MIC, mean ± SD, µg/ml | 0.00 ± 0.01 | 0.00 ± 0.00 | 0.68b |
| Amoxicillin MIC, mean ± SD, µg/ml | 0.29 ± 0.61 | 0.00 ± 0.00 | 0.53b |
| Mean age, mean ± SD, years | 51.10 ± 14.46 | 46.00 ± 14.14 | 0.66b |
| Gender, n (%) | 1a | ||
| Male | 3 (30.0) | 0 (0) | |
| Female | 7 (70.0) | 2 (100) | |
| Smokers, n (%) | 2 (20.0) | 1 (50.0) | 0.45a |
| Alcohol drinkers, n (%) | 4 (40.0) | 0 (0) | 0.51a |
| BMI, mean ± SD, kg/m2 | 22.25 ± 2.52 | 20.96 ± 0.00 | 0.50b |
| Fourth eradication, n (%) | 7 (70) | 2 (100) | 1a |
| Dyspepsia, n (%) | 5 (50.0) | 1 (50.0) | 1a |
| Peptic ulcer, n (%) | 0 (0) | 0 (0) | 1a |
| 14-day regimen | (n = 16) | (n = 1) | |
| H. pylori status | |||
| Presence of mutation in rpoB, n (%) | 2 (12.5) | 0 (0) | 1a |
| Rifabutin MIC, mean ± SD, µg/ml | 0.06 ± 0.25 | 0.00 ± 0.00 | 0.89b |
| Amoxicillin MIC, mean ± SD, µg/ml | 0.07 ± 0.08 | 0.06 ± 0.00 | 0.81b |
| Mean age, mean ± SD, years | 45.69 ± 8.44 | 59 ± 0.00 | 0.15b |
| Gender, n (%) | 1a | ||
| Male | 8 (50.0) | 1 (100) | |
| Female | 8 (50.0) | 0 (0) | |
| Smokers, n (%) | 1 (6.3) | 0 (0) | 1a |
| Alcohol drinkers, n (%) | 8 (50.0) | 0 (0) | 1a |
| BMI, mean ± SD, kg/m2 | 23.20 ± 4.76 | 24.54 ± 0.00 | 0.79b |
| Fourth eradication, n (%) | 10 (62.5) | 1 (100) | 1a |
| Dyspepsia, n (%) | 9 (56.3) | 0 (0) | 0.47a |
| Peptic ulcer, n (%) | 2 (12.5) | 0 (0) | 1a |
BMI: body mass index; H. pylori: Helicobacter pylori; MIC: minimum inhibitory concentration; SD: standard deviation.
Alcohol drinkers were defined as people who consumed at least one drink of alcohol per month.
a
Fisher’s exact test; bStudent’s t-test.