Figure 11.

Schematic illustration of microvesicles encapsulated magnetic nanoparticles and glucose oxidase for dual-stimuli responsive programmable delivery system. The encapsulated glucose-specific enzyme firstly catalyzes glucose into gluconic acid and H₂O₂. The subsequent alternating magnetic field increases the porosity of the polymer shell, leading to the reaction between H₂O₂ and L-arginine to produce nitric oxides. Reproduced with permission from reference ⁷³.