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. 2016 Jun 15;6(9):1353–1361. doi: 10.7150/thno.16093

Scheme 1.

Scheme 1

The iron oxide nanoparticle linked immunosorbent assay (ILISA). (a) Detection probes are constructed by conjugating IONPs with fragmented antibodies. (b) The samples containing target molecules are incubated with capture antibodies immobilized on to a solid support. Surface bound target molecules are detected with the IONP probes. (c) The probes bound to the target molecules were measured using a colorimetric assay. CDS, color development solution.