Figure 1.

Transarterial nanoembolization of heptocellular carcinoma using gold nanoparticles (AuNPs)/Lipiodol for imaging guided photothermal ablation (PTA) of the tumor. A: AuNPs/Lipiodol accumulating in the liver tumor (yellow arrow) after intraarterial injection enabled µCT imaging guided PTA. B: Near-infrared (NIR)-camera recorded a rapid elevation of local temperature up to around 60˚C in the tumor under NIR laser exposure. C: Hematoxylin and eosin staining of the liver and tumor intersection after NIR laser exposure. Massive tumor necrosis was induced after PTA while the adjacent liver appears normal. D: Dark-field microscopy of the same slide revealed that a high concentration of Au accumulated in the necrotic tumor area (T) whereas much less was in the liver (L).