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. 2016 Jun 15;6(9):1425–1439. doi: 10.7150/thno.15359

Figure 2.

Figure 2

The latest version of NanoVelcro CTC Enumeration Assay is performed using (a) a fluidic handler that has been designed and fabricated to introduce processed blood samples into NanoVelcro Chips. (b) Engineering design of NanoVelcro Chips, in which the mechanical click-on approach allows instant assembly of the device. (c) Silanation reaction and NHS chemistry were employed to covalently link streptavidin onto the SiNW substrate, allowing conjugation of biotinylated anti-EpCAM prior to CTC detection studies.