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. 2016 Jun 15;6(9):1425–1439. doi: 10.7150/thno.15359

Figure 4.

Figure 4

1st-Gen. NanoVelcro CTC Assay identified very-small-nuclear CTCs (vsnCTCs) in prostate cancer patients with visceral metastasis. The presence of vsnCTCs has been associated with the presence of visceral metastasis. Serial CTC enumerations also suggested that vsnCTCs emerge before the development/detection of visceral lesions and thus may be a predictive biomarker for visceral metastasis in prostate cancer patients.