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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Metabolism. 2016 Apr 14;65(7):961–967. doi: 10.1016/j.metabol.2016.04.001

Table 2. Meta-analysis of COMT SNP * association with I HbA1c (%) in WGHS and MAGIC.

Study rs4680
 rs4633
 rs4818
β [SE], p-value β [SE], p-value β [SE], p-value
WGHS −0.032 [0.012],
 p = 0.008		 −0.034 [0.012],
 p = 0.005		 −0.029 [0.012],
 p = 0.016
MAGIC −0.006 [0.003],
 p = 0.07		 −0.007 [0.003],
 p = 0.04		 −0.006 [0.007],
 p = 0.4
Fixed −0.008 [0.003],
 p = 0.01		 −0.009 [0.003],
 p = 0.007		 −0.012 [0.006],
 p = 0.05
*

Rs4680 coded allele = G(val), reference allele = A(met); rs4633 coded allele = C, reference allele = T; rs4818 coded allele = G, reference allele = C.