Table 6. Age-adjusted Cox proportional hazard models of COMT rs4680, rs4633, rs4818 effects on type 2 diabetes in the WGHS adjusted for obesity (BMI >30), systolic blood pressure (SBP), triglycerides and hemoglobin A1c (HbA1c).
Rs4680 |
Rs4633 |
Rs4818 |
||||
---|---|---|---|---|---|---|
HR [SE] | p | HR [SE] | p | HR [SE] | p | |
Age-adjusted | 0.92 [0.046] | 0.06 | 0.91 [0.046] | 0.05 | 0.89 [0.047] | 0.017 |
BMI >30 | 0.91 [0.046] | 0.04 | 0.91 [0.047] | 0.03 | 0.88 [0.048] | 0.011 |
SBP | 0.94 [0.046] | 0.17 | 0.93 [0.047] | 0.13 | 0.91 [0.048] | 0.06 |
Triglycerides | 0.93 [0.046] | 0.13 | 0.93 [0.046] | 0.11 | 0.91 [0.047] | 0.06 |
HbA1c | 0.96 [0.046] | 0.36 | 0.96 [0.046] | 0.38 | 0.92 [0.047] | 0.11 |