Table 3.
Antimicrobial Activity of organic extracts from leaves and roots of C. spinosa against selected Gram-positive bacteria.
| C. spinosa Extracts | Bacillus subtilis | Enterococcus faecalis | Micrococcus luteus | Mycobacterium smegmatis | Staphylococcus aureus | Staphylococcus epidermidis | Streptococcus mutans | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MIC | MMC | MIC | MMC | MIC | MMC | MIC | MMC | MIC | MMC | MIC | MMC | MIC | MMC | |
| ChL | 0.19 | 3.12 | 25 | 25 | 0.78 | 1.56 | 6.25 | 12.5 | 0.09 | 0.19 | 6.25 | 12.5 | 6.25 | 25 |
| CL | 1.56 | 12.5 | 25 | 25 | 1.56 | 3.12 | 12.5 | 12.5 | 0.78 | 1.56 | 6.25 | 6.25 | 12.5 | 50 |
| EAL | 1.56 | 1.56 | 12.5 | 12.5 | 0.78 | 3.12 | 6.25 | 12.5 | 6.25 | 50 | 3.12 | 6.25 | 12.5 | 25 |
| ML | 6.25 | 6.25 | 25 | 25 | 1.56 | 3.12 | 12.5 | 25 | 6.25 | >50 | 6.25 | 6.25 | 6.25 | >50 |
| ChR | 0.09 | 0.19 | 25 | 25 | 0.39 | 0.78 | 12.5 | 25 | 3.12 | 12.5 | 6.25 | 12.5 | 12.5 | 50 |
| CR | 0.09 | 0.19 | 25 | 25 | 0.39 | 0.78 | 6.25 | 12.5 | 0.78 | 3.12 | 12.5 | 12.5 | 12.5 | 50 |
| EAR | 0.78 | 0.78 | 6.25 | 6.25 | 0.39 | 1.56 | 6.25 | 12.5 | 1.56 | 12.5 | 3.12 | 6.25 | 6.25 | 25 |
| MR | 3.12 | 3.12 | 25 | 25 | 0.78 | 1.56 | 12.5 | 25 | 6.25 | 25 | 6.25 | 6.25 | 12.5 | >50 |
| Control | MIC | MIC | MIC | MIC | MIC | MIC | MIC | |||||||
| AMP | 0.002 | 0.001 | 0.00012 | 0.004 | 0.004 | 0.004 | 0.00025 | |||||||
| OXA | 0.025 | 0.001 | 0.00012 | 0.002 | 0.00012 | 0.0006 | 0.00012 | |||||||
MIC, Minimal Inhibitory Concentration; MMC, Minimal Microbicidal Concentration; MIC and MMC values are expressed in mg/mL. Cyclohexane extract, ChL; chloroform extract, CL; ethyl acetate extract, EAL: methanolic extract, ML. AMP, ampicillin; OXA, oxacillin.