Skip to main content
. 2016 Feb 25;95(6):635–641. doi: 10.1177/0022034516631973

Figure 2.

Figure 2.

Clinical parameters at baseline and after treatment (3, 6, and 12 mo) for patients subdivided in the 3 clusters: high lipopolysaccharide responders (high levels of INFg, IL6, and IL12p40), mixed (low for first component and high on others markers), and low all (low for all markers tested in the model). Different covariance models examined adjusted for age and baseline clinical parameters showed statistically significant changes among clusters at specific time points and within clusters overall. Cluster 1 (high INF-g, IL-6, IL-12p40) had greater percentage of sites with pocket depth >4 mm (%PD >4 mm), percentage bleeding on probing (BoP), and percentage of affected sites at 3 mo posttreatment versus the other 2 clusters (P < 0.05). Yet, individuals in cluster 3 (i.e., low for all cytokines) had lower mean pocket depth (PD) at 3, 6, and 12 mo posttreatment versus other clusters (P < 0.05) and lower mean clinical attachment levels (CALs) at 3 and 6 mo posttreatment versus other clusters (P < 0.05). *P < 0.05 versus other groups.