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. 2016 May 26;79(6):1679–1683. doi: 10.1021/acs.jnatprod.6b00347

Table 1. Antiparasitic Activities of Natural and Synthetic Phloroglucinols and Analogues.

compound number (this work) IC50 (μM) Dd2 strain compound number (ref (8)) IC50 (μM) FcB1/Columbia strain
1 0.64 ± 0.1a 2 0.75 ± 0.11
5 8.1 ± 0.8 5a 17.6 ± 4.3
6 1.7 ± 0.8 12 6 ± 0.4
7 >10 NRb  
8 >20 NR  
9 >10 NR  
10 >20 NR  
11 1.7 ± 0.4 6 7.4 ± 1.1
12 0.57 ± 0.09 7 4.4 ± 1.3
13 0.56 ± 0.07 NR  
14 >20 NR  
15 >20 NR  
16 >20 NR  
17 6.6 ± 2.4 NR  
18 3.6 ± 0.8 NR  
a

This value differs from that reported in ref (2).

b

NR = not reported in ref (8).