Table 5.
Quality of imputation or genotyping of SNPs presented in Table 2a
arcOGEN | WTCCC2 | Anti‐CCP–negative RA cases | |||||
---|---|---|---|---|---|---|---|
Chr. | SNP ID | Gene | INFOb | Type | INFOb | Type | Genotyping rate, %c |
1 | rs10489912 | NFIA | 1.00 | Directly typed | 1.00 | Directly typed | 99.8 |
1 | rs2249707 | SLAMF9 | 1.00 | Directly typed | 1.00 | Directly typed | 99.9 |
2 | rs10181656 | STAT4 | 0.99 | Imputed | 1.00 | Imputed | 100 |
2 | rs888427 | CYBRD1 | 1.00 | Directly typed | 1.00 | Directly typed | 99.9 |
4 | rs6533712 | CAMK2D | 0.99 | Imputed | 1.00 | Directly typed | 100 |
5 | rs71624119 | ANKRD55 | 0.98 | Imputed | 0.97 | Imputed | 100 |
5 | rs528092 | C5orf30 | 1.00 | Imputed | 1.00 | Imputed | 100 |
6 | rs10440835 | PRL | 0.99 | Imputed | 1.00 | Directly typed | 99.9 |
8 | rs4840565 | BLK | 0.99 | Imputed | 1.00 | Imputed | 100 |
11 | rs613587 | FLI1 | 1.00 | Directly typed | 1.00 | Directly typed | 100 |
16 | rs28698667 | IL27 | 1.00 | Directly typed | 1.00 | Imputed | 99.8 |
17 | rs2689 | HNF1B | 0.99 | Imputed | 1.00 | Imputed | 100 |
18 | rs16955629 | RAB31 | 1.00 | Directly typed | 1.00 | Directly typed | 100 |
21 | rs9979383 | RUNX1 | 1.00 | Directly typed | 1.00 | Directly typed | 99.9 |
SNPs = single‐nucleotide polymorphisms; Chr. = chromosome; WTCCC2 = Wellcome Trust Case Control Consortium 2.
Postimputation INFO score.
Number of anti–citrullinated protein (anti‐CCP)–negative rheumatoid arthritis (RA) patients in the replication data set (UK) with available genotype information after quality control, divided by the total number of individuals (n = 1,024).