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. Author manuscript; available in PMC: 2016 Jun 28.
Published in final edited form as: Oncogene. 2014 Mar 31;34(10):1323–1332. doi: 10.1038/onc.2014.60

Figure 5.

Figure 5

Increased expression of STAT5B and p53 target genes in the platelets of MPN patients. (a) Relative gene expression levels in the platelets of healthy controls (Ctrl, n = 11), essential thrombocythemia (ET, n = 64), primary myelofibrosis (PMF, n = 16) and polycythemia vera (PV, n = 6) patients. P-values indicate the probability that a given expression level is in the range of the normal distribution measured on control samples. (b) Number of polycythemia vera, essential thrombocythemia and primary myelofibrosis patients with increased gene expression levels (Po1e − 3). (c) Number of patients for whom zero, one, two or more genes were significantly increased. (d) Summary of the molecular alterations for patients positive for STAT5B and p53 target genes expression. Numbers in parenthesis are the number of patients in each category.