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Ketamine-induced Fos immunoreactivity (black) in the cholinergic cells labeled by choline acetyltransferase immunoreactivity (purple) in the basal forebrain (A,B) and the orexinergic cells in the medial and lateral perifornical (PeriF) fields of the lateral hypothalamus (C,D). Arrows point to double-labeled cells; arrowheads point to single labeling (without Fos expression). Insets show these same cells at higher magnification. Scale bar = 200 μm.
