. Author manuscript; available in PMC: 2016 Jun 28.

Published in final edited form as: J Comp Neurol. 2008 Jun 1;508(4):648–662. doi: 10.1002/cne.21685

TABLE 2.

Effects of Anesthetics on Tail-Flick Latency (Sec) in Rats With Lesions of the A5–7 Groups or vlPAG

	Baseline	Ketamine (60 mg/kg)	Chloral hydrate (300 mg/kg)	Ethanol (1.0 g/kg)
Control (n = 6)	5.6 ± 0.3	>15	13.8 ± 0.3	10.4 ± 0.6
PAG lesion (n = 6)	5.1 ± 0.3	6.2 ± 0.2^**	6.1 ± 0.2^**	7.0 ± 0.4^**
A5–7 lesion (n = 8)	3.7 ± 0.1^*	5.6 ± 0.3^**	6.0 ± 0.3^**	5.0 ± 0.6^**

P < 0.05 comparing PAG lesion or A5–7 lesion and control state.

^**

P < 0.01 comparing PAG lesion or A5–7 lesion and control state.