Table 3.
Characteristic | N | KRAS | All genes | ||||
---|---|---|---|---|---|---|---|
MT | WT | P | MT | WT | P | ||
Total | 55 | 37 | 18 | 39 | 16 | ||
Age | |||||||
<65 | 29 | 20 | 9 | 1.000 | 22 | 7 | 0.393 |
≥65 | 26 | 17 | 9 | 17 | 9 | ||
Gender | |||||||
Female | 26 | 20 | 6 | 0.166 | 20 | 6 | 0.352 |
Male | 29 | 17 | 12 | 19 | 10 | ||
Location | |||||||
C18-19 | 35 | 25 | 10 | 0.358 | 26 | 9 | 0.466 |
C20 | 20 | 12 | 8 | 13 | 7 | ||
Side | |||||||
Right | 12 | 10 | 2 | 0.289 | 10 | 2 | 0.284 |
Left | 43 | 27 | 16 | 29 | 14 | ||
Type of adenocarcinoma | |||||||
Adenocarcinoma | 44 | 26 | 18 | 0.010 | 28 | 16 | 0.023 |
Mucinous | 11 | 11 | 0 | 11 | 0 | ||
Tumour budding | |||||||
Yes | 21 | 15 | 6 | 0.606 | 16 | 5 | 0.498 |
No | 34 | 22 | 12 | 23 | 11 | ||
Extrahepatic metastases | |||||||
Yes | 34 | 23 | 11 | 0.938 | 25 | 9 | 0.586 |
No | 21 | 14 | 7 | 14 | 7 | ||
Lung metastases | |||||||
Yes | 20 | 13 | 7 | 0.786 | 15 | 5 | 0.614 |
No | 35 | 24 | 11 | 24 | 11 | ||
Peritoneal metastases | |||||||
Yes | 8 | 5 | 3 | 0.756 | 6 | 2 | 0.783 |
No | 47 | 32 | 15 | 33 | 14 | ||
Lymphnode metastases | |||||||
Yes | 12 | 7 | 5 | 0.455 | 8 | 4 | 0.714 |
No | 43 | 30 | 13 | 31 | 12 | ||
Treatment arm | |||||||
FOLFOX4 | 26 | 19 | 7 | 0.389 | 19 | 7 | 0.738 |
FOLFOX4 + bevacizumab | 29 | 18 | 11 | 20 | 9 |