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. 2016;23(1):24–34. doi: 10.6001/actamedica.v23i1.3267

Table 3.

The association of KRAS and all gene (KRAS, BRAF, NRAS, PIK3CA) mutations with clinical and pathological characteristics

Characteristic N KRAS All genes
MT WT P MT WT P
Total 55 37 18 39 16
Age
<65 29 20 9 1.000 22 7 0.393
≥65 26 17 9 17 9
Gender
Female 26 20 6 0.166 20 6 0.352
Male 29 17 12 19 10
Location
C18-19 35 25 10 0.358 26 9 0.466
C20 20 12 8 13 7
Side
Right 12 10 2 0.289 10 2 0.284
Left 43 27 16 29 14
Type of adenocarcinoma
Adenocarcinoma 44 26 18 0.010 28 16 0.023
Mucinous 11 11 0 11 0
Tumour budding
Yes 21 15 6 0.606 16 5 0.498
No 34 22 12 23 11
Extrahepatic metastases
Yes 34 23 11 0.938 25 9 0.586
No 21 14 7 14 7
Lung metastases
Yes 20 13 7 0.786 15 5 0.614
No 35 24 11 24 11
Peritoneal metastases
Yes 8 5 3 0.756 6 2 0.783
No 47 32 15 33 14
Lymphnode metastases
Yes 12 7 5 0.455 8 4 0.714
No 43 30 13 31 12
Treatment arm
FOLFOX4 26 19 7 0.389 19 7 0.738
FOLFOX4 + bevacizumab 29 18 11 20 9