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. 2016 Feb 23;7(12):13400–13415. doi: 10.18632/oncotarget.7630

Figure 2. The interaction between diet and T. cruzi infection enhances the development of cardiovascular disorders.

Figure 2

Lipid metabolism was analyzed by the measurements of plasma levels of A. triglycerides and B. total cholesterol after 12h fasting in mice from either LFD, DIO, DIO+I or LFD+I groups. C. Lipoprotein pattern was assessed by electrophoresis. ApoB100 was quantified at 24 weeks and analyzed by one-way ANOVA: DIO, DIO+I and LFD+I vs. LFD: * p < 0.05. D. A representative hematoxylin and eosin image of heart tissue from each group is shown (400x). The arrows represent inflammatory foci (white) and lipid deposition (black). Scale bar = 20μm. E. A representative hematoxylin and eosin image of abdominal aorta from each group is shown (400x). The arrows represent inflammatory foci (white) and lipid deposition (black). Data are shown as mean ± SEM of seven mice per group from one experiment representative of two performed. Statistical analysis was made by using two-way ANOVA test as follows: DIO vs. LFD: *** p < 0.001, ** p < 0.01, * p < 0.05, and DIO vs. DIO+I: ф p < 0.05, ффф p < 0.001.