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. 2016 Feb 11;7(12):13706–13716. doi: 10.18632/oncotarget.7333

Figure 6. Correlation between TAZ and MRTF/SRF pathway in the TCGA breast cancer database.

Figure 6

(A) TAZ expression level is correlated with the expression level of MRTF/SRF target genes in breast cancer. Co-expression data between TAZ and FLNA, SRF, MYH9, and VCL, respectively, in the breast cancer TCGA RNA-seq data were extracted from the cbioportal database. The value of Pearson's correlation coefficient and Spearman's correlation coefficient were generated by the cbioportal database to measure the correlation of gene co-expression. (B) The expression levels of TAZ and MRTF/SRF target genes in the TCGA datasets from UCSC Cancer genomics browser were shown. (C) The expression levels of MRTF/SRF target genes are positively associated with basal marker CDH3 and negatively correlated with luminal marker ESR1. Co-expression data in the breast cancer TCGA RNA-seq data were extracted from the cbioportal database.