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. 2016 Feb 13;7(12):13965–13975. doi: 10.18632/oncotarget.7369

Table 1. IC50 values of the cyclometallated iridium(III) compounds 1–6 against the p53/hDM2 interaction as determined by a FA assay.

Cyclometallated iridium(III) compounds IC50/μM
1 16 (± 5)
2 No noticeable binding
3 No noticeable binding
4 No noticeable binding
5 21 (± 5)
6 33 (± 3)