Table 1. IC50 values of the cyclometallated iridium(III) compounds 1–6 against the p53/hDM2 interaction as determined by a FA assay.
Cyclometallated iridium(III) compounds | IC50/μM |
---|---|
1 | 16 (± 5) |
2 | No noticeable binding |
3 | No noticeable binding |
4 | No noticeable binding |
5 | 21 (± 5) |
6 | 33 (± 3) |