Figure 1. Comparison of quantitative clinicopathologic parameters according to MLH1 promoter methylation status in CIMP-H CRC (n = 65).
A. Age at diagnosis. B. Tumor location bowel subsite. C. Tumor-infiltrating lymphocyte density (number of tumor-infiltrating lymphocytes/high power field). D. Size of the largest Crohn-like lymphoid aggregate (μm). E. Crohn-like lymphoid reaction density (number of lymphoid aggregates/mm). F. Number of methylated CIMP markers (except for MLH1). Abbreviations: TIL, tumor-infiltrating lymphocyte; HPF, high power field; LA, lymphoid aggregate.