Figure 1. Neurite outgrowth of PC12E2 cells grown on monolayer of fibroblasts L929.
(A) Confocal images of PC12E2 cells transiently transfected with empty vector pCMV5 (upper panel) or pCMV5-APP (lower panel) and grown on monolayer of NCAM-negative fibroblasts (left panel) or NCAM-positive fibroblasts (right panel). (B) Quantification of the neurite length of PC12E2 cells. Neurite length of PC12E2 transfected with empty vector and grown on NCAM-negative fibroblasts was set to 100%. *p < 0.05, **p < 0.01.
