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. 2016 Feb 12;7(12):14199–14206. doi: 10.18632/oncotarget.7348

Figure 4. Secreted APP and NCAM potentiated neurite outgrowth.

Figure 4

(A) Confocal images of hippocampal neuron seeded on monolayer of NCAM-negative fibroblasts (left panel) or NCAM-positive fibroblasts (right panel) and maintained in the medium containing secreted APP (lower panel) or PBS (upper panel) as the control. (B) Quantification of the neurite length in response to the treatment of secreted APP and NCAM on neurite outgrowth. Neurite length of hippocampal neurons grown on NCAM-negative fibroblasts L929, and maintained in medium containing PBS was set to 100%. *p < 0.05, **p < 0.01.