Table 1. The univariate analysis of the risk factors predicting the survival period (log-rank test).

Factors	Median survival (day)	P
Sex
Male	205 (11–698)
Female	285 (124–790)	0.0408
Age
< 68	235 (11–651)
≥ 68	230 (60–790)	0.2810
HSP27 expression level score
Low	223 (11–651)
High	268 (106–790)	0.1186
Positive ratio of p-HSP27
Low	205 (11–651)
High	275 (110–790)	0.0158
Metastasis
M0	285 (11–790)
M1	205 (22–584)	0.0133
Histological type
Poor	180 (124–292)
Well-Mod	274 (11–790)	0.0016
Response to Chemotherapy
PD	207 (11–584)
PR–SD	303 (133–790)	0.0116

Abbreviations: p-HSP27: Phosphorylated HSP27

M0: Distant metastasis (−)

M1: Distant metastasis (+)

Well: Well-differentiated adenocarcinoma

Mod: Moderately differentiated adenocarcinoma

Poor: Poorly differentiated adenocarcinoma

PR: Partial response

SD: Stable disease

PD: Progressive disease.