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. 2016 Feb 13;7(12):14324–14335. doi: 10.18632/oncotarget.7365

Figure 1. Overview of LED/Laser devices, and decrease in IR700-fluorescence induced by either LED or Laser.

Figure 1

(A) The NIR Laser system, and LED system used in this study. (B) Character of wavelength of LED and Laser-light in reference to the absorption of IR700 dye (C) The decrease in IR700-fluorescence was greater with Laser than LED at the same energy level (upper: fluorescence 700 nm, lower: white image). The decrease of IR700-fluorescence was detected in a dose dependent manner. (D) Quantification of fluorescence mean intensity showed a larger decrease with Laser-light than LED at the same dose (n = 5, *P < 0.01, **P < 0.001, ***P < 0.0001). (E) A greater decrease of IR700-fluorescence after Laser-light vs. LED-light was detected with spectroscopy.