Skip to main content
. 2016 Feb 13;7(12):14324–14335. doi: 10.18632/oncotarget.7365

Figure 2. In vitro NIR-PIT effect with LED or Laser.

Figure 2

(A) A431 and MDA-MB-468-luc cells were co-cultured with 3T3/DsRed (non-HER expressing) cells. They were treated with pan-IR700 and observed by microscopy (before and after irradiation with either Laser or LED NIR-light. Target specific necrotic cell death was observed after excitation with NIR-light (after 30 min). No damage was demonstrated in 3T3/DsRed cells with LED or Laser. *3T3/DsRed cells, Bar = 50 μm. (B) Luciferase activity in MDA-MB-468-luc cells decreased after both LED and Laser mediated NIR-PIT in a light dose-dependent manner. Significant differences between LED and Laser were detected. (n = 4; ***P < 0.01).