Figure 2. Immune-related biological processes and pathways are enriched in “favorable outcome signature”.

A. Most highly enriched Gene Ontology (GO) terms according to Gene Ontology Consortium and REVIGO algorithms (see Materials and Methods). GO terms are represented by tiles, grouped and colored according to semantic similarities to other GO terms. Tile areas are proportional to −log₁₀ p-value for each term. B. 2-D heatmap view of top-30 canonical pathways and their genes identified by Ingenuity Pathway Analysis. Pathways are ranked by multiple hypothesis corrected p-values. Associations between FOS genes and each pathway are indicated with red; immune-related pathways are in red.