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A. MCF7 cells were incubated for 3 days with indicated doses of doxorubicin, nutlin-3 and GSK2830371 and expression of indicated genes was determined by qRT-PCR. Levels are presented as the ratio of mRNA to GAPDH mRNA and are normalized to untreated cells. Error bars correspond to SEM. B. MCF7 cells were incubated as in A and expression of selected proteins was analysed by immunoblotting.
