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A. TEM image of the mesoporous silica nanoparticle (MSNP) core (scale bar = 50 nm). B. Schematic of surface modification of MSNP (layer-by-layer) with cross-linked polyethylenimine (PEI), polyethyleneglycol (PEG), trastuzumab, and siRNA. C. Hydrodynamic size distribution of T-NP (blue line) and with siRNA loading (black line).
