Table 1b. LOX- 1 protein expression, detected by immunohistochemistry, in human tumors and controls.
| A | B | C | D | |
|---|---|---|---|---|
| CRC | CRC | ALGD | NM | |
| G2-G3; any T; | G1-G2; any T; N0 | |||
| N1,N2, M0, M1 | ||||
| % (n=10) | % (n=18) | % (n=8) | % (n=36) | |
| LOX-1 | ||||
| Neg Neg/Weak | 0 | 0 | 25(2) | 94.4(34) |
| Pos Moderate | 10(1) | 23(5) | 75(6) | 5.5(2) |
| Strong | 90(9) | 72(13) | 0 | 0 |
Number of cases was shown as a percentage. In parentheses, the absolute numbers were reported.
CRC: colorectal adenocarcinomas; ALGD: adenomas with low-grade dysplasia. Distant normal mucosa (NM) of the same patients was used as control.
Significance all data Ptot<0.001; A vs D: P<0.001; B vs D: P<0.001; C vs D: P<0.001