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. 2016 Feb 19;7(12):14940–14950. doi: 10.18632/oncotarget.7496

Figure 2. ABCB5 regulates murine melanoma growth and drug resistance.

Figure 2

A. mRNA levels of ABCB5 from B16F10 lysates following transfection of shRNA constructs. Data are presented as mean ± SD. **P < 0.01 for control shRNA versus shABCB5. B. Western blot for ABCB5 expression by B16F10 (scrambled) vs. B16F10 (shABCB5). C. The tumor growth curve of B16F10 (scrambled) and B16F10 (shABCB5) (n = 6 each). Data are presented as mean ± SD. **P < 0.01 for B16F10 (scrambled) versus B16F10 (shABCB5). D. Drug dependent cell killing of B16F10 (shABCB5) versus B16F10 (scrambled).*for P < 0.05, ** for P < 0.01.